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Re: Side Effects

Von: andrea buccioni (buccionia@tiscali.it) [Profil]
Datum: 15.02.2007 10:57
Message-ID: <C1F9ED2A.AD99%buccionia@tiscali.it>
Newsgroup: it.sport.calcio it.hobby.motociclismo alt.support.hepatitis-c
Capperi oh. un problema serio e neanche una considerazione.
Proprio vero che il 95 per cento della popolazione vive di falsi
problemi tipo una partita di calcio o una gomma a terra...
che mondo dozzinale.

> piuma14-02-2007
> 21:49lapiumetta12@alice.it45d375cd$0$4791$4fafbaef@reader4.news.tin.it ha
> perso la testa in una brocca di Asti e seduto sulla tinozza vaneggia
> scrivendo:

>> "Waterspider" <waterspider@moonlight.net> ha scritto nel
messaggio
>> news:12t6saps99btf1a@corp.supernews.com...
>>
>> <elmoemerson@webtv.net> wrote in message
>> news:22230-45D3174B-4@storefull-3251.bay.webtv.net...
>>> Here's what you can expect, Guy.
>>>
>>> In the fourth week, all your hair is gonna drop out. The fifth week your
>>> teeth turn green. Then you get uncontrollable vomiting and diarrhea.
>>> Migraines start about the eighth week. The whole time your abdomen is
>>> turning black from all the tissue necrosis at the shot sites. About the
>>> 10th week, you'll crash your car into the back of a schoolbus because
>>> you're so spaced out. The 11th week gives you some relief because of the
>>> pain killers they are giving you in the hospital for the broken pelvis
>>> you suffered in the accident. But now you have dragon breath and noone
>>> will come visit you in the hospital. More relief the next two weeks.
>>> Still in the hospital because of the staph infection you got from the
>>> compound fracture in the accident. The bill already came for the first
>>> month of television while in the hospital. Work calls today and says
>>> that you were fired. Finally out of the hospital in the 23rd week. Your
>>> muscles have atrophy to the point you can barely lift your head anymore.
>>> Back pains and hallucinations begin about the 28th week. Your family has
>>> told you not to come over anymore til you feel better. Mom didn't
>>> appreciate being hit in the face with the creme pie. In the 30th week,
>>> palpatations and twitches and belching fart gas drive you to the doctor.
>>> He just says they are not due to the hep, sorry. Long, gray hair begins
>>> to grow from your forehead but the rest of your hair is long gone by
>>> now. In the 40th week you spend the night in jail for assaulting the
>>> produce clerk at the local grocery store, That makes 4 lawsuits pending
>>> against you now. One for the auto accident (DUI), one suit by the
>>> township for knocking down the traffic light post, and a fourth suit by
>>> the produce clerk. In your 44th week you get more relief. It suddenly
>>> occurs to you that you don't remember ANYTHING anymore. You can't go
>>> anywhere without being led by the hand. You will overhear a guy at a
>>> restaurant who has serious Alzheimer Disease say, "Man, that guy is
one
>>> fucked up dude." On the way out of the restaurant you will stumble in
>>> the parking lot and split the back of your pants out. By the 47th week,
>>> they are giving you your shots in your scalp, you need skin grafts on
>>> your abdomen when you finally come off treatment. Just when you think
>>> you have come to the end of the road and it's your last shot, you get an
>>> allergic reaction to the meds and spend the next 7 weeks in the
>>> hospital. It will take a long time for your trachea to heal completely
>>> from being ripped open when they insert the endotracheal tube during
>>> surgery. You will celebrate the end of your ordeal with a new bag of IV
>>> fluids. Then your kidneys will shut down, your thyroid will say 'adios
>>> amigo', you will get serious lifelong tremors and the uncontrollable
>>> urge to fart in public. The hairs growing from your nose will need
>>> trimming every day, they will grow over an inch each night while you
>>> sleep.
>>> You will look back after they give you the good news you're still
>>> undetectable six months post treatment and recall that the treatment
>>> wasn't all that bad. You didn't lose too much of your savings from the
>>> law suit settlements nor do you need anymore surgeries (5 was enough!).
>>> Thank God for amnesia and bankruptcy laws. It will have been a long,
>>> strange trip.
>>> Good luck, Elmo
>>>
>> This is an accurate description of treatment without doing anything to
>> counteract the side-effects. Fortunately, modern medicine is available to
>> get us through this. I know that I wouldn't have been able to complete tx
>> without it.
>>
>> To counteract the nausea, smoke pot or eat special brownies. It will
>> settle your stomach; chemo patients all over the world know this.
>> To counteract the twitches and tremors, smoke more pot.
>> To counteract the feelings of rage and aggression (riba-rage), smoke more
>> pot.
>> To counteract the depression and suicide ideation, smoke more pot.
>> To counteract the insomnia, smoke more pot. If it doesn't do the trick,
>> eat Gravol because it's an antihistamine and should knock you out.
>> Now you must drink lots of water, because the antihistamine will dehydrate
>> you. Drink more water, if you're still awake.
>> Have another toke, and drink more water to relieve your dry mouth and
>> throat.
>> Put a Pee Bucket beside your bed, because you'll wake up with an
>> unconrolable urge to urinate. Of course you will, you've drank enough
>> water to float a freakin' battleship, and you're so stoned from all the
>> pot and Gravol that you wouldn't be able to find the bathroom, never mind
>> drag your sorry ass out of bed.
>> And, you're suffering from fatigue, serious fatigue. Well, why not? You've
>> been so stoned that you've forgotten to eat.
>> Never mind, drink more water and go back to sleep.
>> Try to remember that there's a bucket of pee beside your bed.
>>
>>
>
> Central nervous system involvement in patients with HCV-related
>
> cryoglobulinemia: review and a case report
>
> D. Filippini, F. Colombo, S. Jann1 , R. Corneo2, B. Canesi
>
> Divisione di Reumatologia, 1Divisione di Neurologia, 2Servizio
> Immuno-Trasfusionale
>
> Ospedale Niguarda Cr´ Granda, Milano
>
>
>
> SUMMARY
>
> Introduction: Few well-documented cases of central nervous system
> involvement in patients with mixed cryoglobulinemia
>
> and/or HCV infection have been reported. We can distinguish between acute or
> subacute diffuse and focal lesions (transient
>
> ischemic attack-like syndromes and cerebrovascular accidents).
>
> Methods: A search of two electronic databases (Medline and EMBASE) was
> conducted from the year of their inception
>
> (1966 for Medline and 1988 for EMBASE) to September 2000. The search
> strategy employed entailed combining
>
> these terms: Cryoglobulinemia, Central Nervous System, Hepatitis C, chronic
> hepatitis. Cryoglobulinemia and Central
>
> Nervous System were also used as free test words. We analysed articles with
> case reports and the most frequent
>
> articles on the references list.
>
> Pathogenesis: The main pathophysiologic mechanism of cerebral involvement is
> ischemia (or rarely hemorrhage) due
>
> to diffuse or segmental vasculitis of the small cerebral vessels. In these
> cases a brain MRI usually shows single or multiple
>
> increased T2 signals. Furthermore an occasional occlusive vasculopathy
> without vasculitis was documented histologically.
>
> In these patients ischemia could be started or enhanced by the engorgement
> of the microvasculature by
>
> clumps of red cells and by aggregates of cryoglobulins. In the same patients
> vasculitis and hemoreological abnormalities
>
> can affect the clinical picture of the cerebral involvement in mixed
> cryoglobulinemia. Finally, the detection
>
> of HCV in the lesions induces a hypothesis that, in some cases, CNS
> involvement could be directly related to chronic
>
> HCV infection, even in the absence of cryoglobulin production.
>
> Case report: We describe a 63 year-old woman with acute severe
> encephalopathy. Laboratory evaluation revealed a
>
> high positive test result for rheumatoid factor (3390 U/ml) and
> hypocomplementemia (C4 less than 1.67 mg/dl). Protein
>
> immunofixation electrophoresis demonstrated 5% monoclonal proteins (IgM/k
> and IgG/k), 3% cryoglobulins were
>
> present, HCV antibody and HCV-RNA (type 2a-2c) were positive. Cryoglobulins
> were never typed, because they disappeared
>
> after plasma exchanges. Liver enzymes, renal function and findings on
> cerebrospinal fluid were normal. Cerebral
>
> CT and MRI were also normal. Antinuclear antibodies, anti nDNA antibodies,
> antiphospholipid antibodies, lupus
>
> anticoagulant, ANCA, Lyme disease serology, complete tests for thrombophilia
> were negative. Bone aspiration
>
> was normal. The patient, in coma, was treated with two plasma exchanges.
> During the first treatment she recovered
>
> consciousness. Prednisone (1 mg/Kg/day) and cyclophosphamide (400 mg iv for
> three days) were added. After a week
>
> two plasma exchanges were performed again. Liver enzymes and rheumatoid
> factor were analyzed monthly for six
>
> months and than every two months for another six month period up to the
> present. Liver enzymes were always normal,
>
> rheumatoid factor was always at a lower level than the first evaluation (now
> it's 311 U/ml). At present she is taking
>
> Prednisone 5 mg once a day, neurologic syntoms are absent and neurologic
> examination is normal.
>
> Discussion: We can conclude that: central neurologic involvement may be the
> clinical presentation of HCV infection
>
> and mixed cryoglobulinemia. HCV serologic tests and cryoglobulins should be
> considered in patient with encephalopathy
>
> of non-obvious cause; plasma exchange is the treatment of choice in acute
> severe forms; in some patients
>
> HCV could involve directly CNS, even in the absence of cryoglobulin
> production.
>
>


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