Re: Side Effects
Von: andrea buccioni (buccionia@tiscali.it) [Profil]
Datum: 15.02.2007 10:57
Message-ID: <C1F9ED2A.AD99%buccionia@tiscali.it>
Newsgroup: it.sport.calcio it.hobby.motociclismo alt.support.hepatitis-c
Datum: 15.02.2007 10:57
Message-ID: <C1F9ED2A.AD99%buccionia@tiscali.it>
Newsgroup: it.sport.calcio it.hobby.motociclismo alt.support.hepatitis-c
Capperi oh. un problema serio e neanche una considerazione. Proprio vero che il 95 per cento della popolazione vive di falsi problemi tipo una partita di calcio o una gomma a terra... che mondo dozzinale. > piuma14-02-2007 > 21:49lapiumetta12@alice.it45d375cd$0$4791$4fafbaef@reader4.news.tin.it ha > perso la testa in una brocca di Asti e seduto sulla tinozza vaneggia > scrivendo: >> "Waterspider" <waterspider@moonlight.net> ha scritto nel messaggio >> news:12t6saps99btf1a@corp.supernews.com... >> >> <elmoemerson@webtv.net> wrote in message >> news:22230-45D3174B-4@storefull-3251.bay.webtv.net... >>> Here's what you can expect, Guy. >>> >>> In the fourth week, all your hair is gonna drop out. The fifth week your >>> teeth turn green. Then you get uncontrollable vomiting and diarrhea. >>> Migraines start about the eighth week. The whole time your abdomen is >>> turning black from all the tissue necrosis at the shot sites. About the >>> 10th week, you'll crash your car into the back of a schoolbus because >>> you're so spaced out. The 11th week gives you some relief because of the >>> pain killers they are giving you in the hospital for the broken pelvis >>> you suffered in the accident. But now you have dragon breath and noone >>> will come visit you in the hospital. More relief the next two weeks. >>> Still in the hospital because of the staph infection you got from the >>> compound fracture in the accident. The bill already came for the first >>> month of television while in the hospital. Work calls today and says >>> that you were fired. Finally out of the hospital in the 23rd week. Your >>> muscles have atrophy to the point you can barely lift your head anymore. >>> Back pains and hallucinations begin about the 28th week. Your family has >>> told you not to come over anymore til you feel better. Mom didn't >>> appreciate being hit in the face with the creme pie. In the 30th week, >>> palpatations and twitches and belching fart gas drive you to the doctor. >>> He just says they are not due to the hep, sorry. Long, gray hair begins >>> to grow from your forehead but the rest of your hair is long gone by >>> now. In the 40th week you spend the night in jail for assaulting the >>> produce clerk at the local grocery store, That makes 4 lawsuits pending >>> against you now. One for the auto accident (DUI), one suit by the >>> township for knocking down the traffic light post, and a fourth suit by >>> the produce clerk. In your 44th week you get more relief. It suddenly >>> occurs to you that you don't remember ANYTHING anymore. You can't go >>> anywhere without being led by the hand. You will overhear a guy at a >>> restaurant who has serious Alzheimer Disease say, "Man, that guy is one >>> fucked up dude." On the way out of the restaurant you will stumble in >>> the parking lot and split the back of your pants out. By the 47th week, >>> they are giving you your shots in your scalp, you need skin grafts on >>> your abdomen when you finally come off treatment. Just when you think >>> you have come to the end of the road and it's your last shot, you get an >>> allergic reaction to the meds and spend the next 7 weeks in the >>> hospital. It will take a long time for your trachea to heal completely >>> from being ripped open when they insert the endotracheal tube during >>> surgery. You will celebrate the end of your ordeal with a new bag of IV >>> fluids. Then your kidneys will shut down, your thyroid will say 'adios >>> amigo', you will get serious lifelong tremors and the uncontrollable >>> urge to fart in public. The hairs growing from your nose will need >>> trimming every day, they will grow over an inch each night while you >>> sleep. >>> You will look back after they give you the good news you're still >>> undetectable six months post treatment and recall that the treatment >>> wasn't all that bad. You didn't lose too much of your savings from the >>> law suit settlements nor do you need anymore surgeries (5 was enough!). >>> Thank God for amnesia and bankruptcy laws. It will have been a long, >>> strange trip. >>> Good luck, Elmo >>> >> This is an accurate description of treatment without doing anything to >> counteract the side-effects. Fortunately, modern medicine is available to >> get us through this. I know that I wouldn't have been able to complete tx >> without it. >> >> To counteract the nausea, smoke pot or eat special brownies. It will >> settle your stomach; chemo patients all over the world know this. >> To counteract the twitches and tremors, smoke more pot. >> To counteract the feelings of rage and aggression (riba-rage), smoke more >> pot. >> To counteract the depression and suicide ideation, smoke more pot. >> To counteract the insomnia, smoke more pot. If it doesn't do the trick, >> eat Gravol because it's an antihistamine and should knock you out. >> Now you must drink lots of water, because the antihistamine will dehydrate >> you. Drink more water, if you're still awake. >> Have another toke, and drink more water to relieve your dry mouth and >> throat. >> Put a Pee Bucket beside your bed, because you'll wake up with an >> unconrolable urge to urinate. Of course you will, you've drank enough >> water to float a freakin' battleship, and you're so stoned from all the >> pot and Gravol that you wouldn't be able to find the bathroom, never mind >> drag your sorry ass out of bed. >> And, you're suffering from fatigue, serious fatigue. Well, why not? You've >> been so stoned that you've forgotten to eat. >> Never mind, drink more water and go back to sleep. >> Try to remember that there's a bucket of pee beside your bed. >> >> > > Central nervous system involvement in patients with HCV-related > > cryoglobulinemia: review and a case report > > D. Filippini, F. Colombo, S. Jann1 , R. Corneo2, B. Canesi > > Divisione di Reumatologia, 1Divisione di Neurologia, 2Servizio > Immuno-Trasfusionale > > Ospedale Niguarda Cr´ Granda, Milano > > > > SUMMARY > > Introduction: Few well-documented cases of central nervous system > involvement in patients with mixed cryoglobulinemia > > and/or HCV infection have been reported. We can distinguish between acute or > subacute diffuse and focal lesions (transient > > ischemic attack-like syndromes and cerebrovascular accidents). > > Methods: A search of two electronic databases (Medline and EMBASE) was > conducted from the year of their inception > > (1966 for Medline and 1988 for EMBASE) to September 2000. The search > strategy employed entailed combining > > these terms: Cryoglobulinemia, Central Nervous System, Hepatitis C, chronic > hepatitis. Cryoglobulinemia and Central > > Nervous System were also used as free test words. We analysed articles with > case reports and the most frequent > > articles on the references list. > > Pathogenesis: The main pathophysiologic mechanism of cerebral involvement is > ischemia (or rarely hemorrhage) due > > to diffuse or segmental vasculitis of the small cerebral vessels. In these > cases a brain MRI usually shows single or multiple > > increased T2 signals. Furthermore an occasional occlusive vasculopathy > without vasculitis was documented histologically. > > In these patients ischemia could be started or enhanced by the engorgement > of the microvasculature by > > clumps of red cells and by aggregates of cryoglobulins. In the same patients > vasculitis and hemoreological abnormalities > > can affect the clinical picture of the cerebral involvement in mixed > cryoglobulinemia. Finally, the detection > > of HCV in the lesions induces a hypothesis that, in some cases, CNS > involvement could be directly related to chronic > > HCV infection, even in the absence of cryoglobulin production. > > Case report: We describe a 63 year-old woman with acute severe > encephalopathy. Laboratory evaluation revealed a > > high positive test result for rheumatoid factor (3390 U/ml) and > hypocomplementemia (C4 less than 1.67 mg/dl). Protein > > immunofixation electrophoresis demonstrated 5% monoclonal proteins (IgM/k > and IgG/k), 3% cryoglobulins were > > present, HCV antibody and HCV-RNA (type 2a-2c) were positive. Cryoglobulins > were never typed, because they disappeared > > after plasma exchanges. Liver enzymes, renal function and findings on > cerebrospinal fluid were normal. Cerebral > > CT and MRI were also normal. Antinuclear antibodies, anti nDNA antibodies, > antiphospholipid antibodies, lupus > > anticoagulant, ANCA, Lyme disease serology, complete tests for thrombophilia > were negative. Bone aspiration > > was normal. The patient, in coma, was treated with two plasma exchanges. > During the first treatment she recovered > > consciousness. Prednisone (1 mg/Kg/day) and cyclophosphamide (400 mg iv for > three days) were added. After a week > > two plasma exchanges were performed again. Liver enzymes and rheumatoid > factor were analyzed monthly for six > > months and than every two months for another six month period up to the > present. Liver enzymes were always normal, > > rheumatoid factor was always at a lower level than the first evaluation (now > it's 311 U/ml). At present she is taking > > Prednisone 5 mg once a day, neurologic syntoms are absent and neurologic > examination is normal. > > Discussion: We can conclude that: central neurologic involvement may be the > clinical presentation of HCV infection > > and mixed cryoglobulinemia. HCV serologic tests and cryoglobulins should be > considered in patient with encephalopathy > > of non-obvious cause; plasma exchange is the treatment of choice in acute > severe forms; in some patients > > HCV could involve directly CNS, even in the absence of cryoglobulin > production. > >[ Auf dieses Posting antworten ]
